It is proven that CBD could help to deal with myriads of health conditions, including pain. When you have chronic pain, it is possibly daunting to consume a new supplement. Luckily, CBD is not habit-forming and not psychoactive, plus it is safer to use than standard prescription drugs. This means it is also safer as compared to painkillers that doctors often prescribe. So should you consider using CBD for pain? Early research and anecdotal evidence indicate that you should do it. Here, we will look at how it can ease pain.
In What Way Does Cannabidiol Work?
The human endocannabinoid system is the source of cannabidiol’s beneficial effects. CBD can activate the ECS in an indirect way. A biological network of receptors and neurons form the ECS, and it is present in brain parts such as the hypothalamus, hippocampus and nucleus accumbens. The ECS aids in regulating mood, appetite, memory, and pain. The neuroscience behind pain centers and pain may not be completely understood even today. However, scientists are aware that by making some of the body receptors active, cannabidiol can reduce inflammation, and thereby, pain.
In What Specific Way Does It Ease Chronic Pain?
A study from 2007 revealed that repeated use of cannabidiol eased the pain and swelling related to the sciatic nerves of rats in a way that depends on the dosage. Researchers thought that this happened through the process that stimulated TRPV1 receptors, or that activated an endocannabinoid known as anandamide. Cannabidiol gets the therapeutic capability of it with the indirect stimulation of numerous different receptors. Cannabidiol does not make CB1 cannabinoid receptors active as tetrahydrocannabinol does.
Kentucky-based researchers discovered that the transdermal administration of cannabidiol in high dosages to rats diagnosed with arthritis over a week, considerably reduced joint inflammation. This happened since cannabidiol appeared to minimize pro-inflammatory biomarkers, which are in essence molecules that produce inflammation. The rodents had experienced reduced pain reactions, most possibly a result of the lessened inflammation. A different study showed that cannabidiol use lessened joint inflammation of rats with osteoarthritis and that it had neuroprotective effects. Researchers attributed this to reduced leukocytes adjacent to the joint area.
Researchers have also examined how cannabidiol could ease neuropathic pain. Last year, researchers from Canada discovered that repeated cannabidiol administration reduced allodynia and that it also lessened rat behavior similar to anxiety. CBD provides the therapeutic effects of it by acting on the receptors associated with immune reactions, plus TRPV1 receptors. In the 2019 study, it helped to reduce the said behavior of the rodents by working with serotonin receptors. These receptors may be popular for the effect on mental depression and antidepressants, but serotonin regulates anxiety, gastrointestinal motility, sleep, appetite and numerous other bodily functions.
So cannabidiol might just treat pain and a certain level of anxiety associated with the pain.
Safety And Secondary Effects
So, should you say yes to CBD pain relief option? You should. That said, you also have to be aware of the secondary negative effects of it, no matter how minor these are. Changes in weight, diarrhea, dry mouth and tiredness are among its side effects. Anyhow, even the World Health Organization states that cannabidiol has a good safety profile and that it is generally a well-tolerated substance. It is also shown that cannabidiol could help to deal with addiction, or the tendency to reuse standard substances such as nicotine or prescription medication like painkillers.
Opioid receptors lie near the human endocannabinoid system, which may modulate their activity. This fact augurs well for those looking to treat pain in a safe manner. It gives an individual further products to deal with his or her pain in manners involving less risk.
Finding An Effective Treatment
Whichever form of CBD product you may use, you should be able to ease the pain with it. However, some forms of it are better than others in regards to this health issue. Which the best CBD for pain is, depends on what kinds of effects you are seeking. For instance, if you wish not to have any trace of tetrahydrocannabinol in the body, then a CBD topical product might be the best option for you.
However, the topical type item does not offer a whole-body relief such as, say, CBD transdermal patch does. Then again, the latter product will not act as fast as the former. The same applies to CBD gummies, but these edible candies deliver a dose of cannabidiol that will last longer than the other forms of it. All forms of cannabidiol products have their relative benefits and disadvantages, and every single individual has their own preferences. No matter which one you select, you should consider starting at a low dosage and increasing it gradually until finding the ideal dose for you.